Lactulose is the Generic Name and Constulose, Kristalose, Chronulac, Cephulac, Constilac, Cholac, Duphalac, Evalose, Heptalac, Enulose, Generlac are some of the Brand Names for Lactulose.

What is Lactulose?

Lactulose is a laxative used to treat constipation and a type of sugar. It is broken down in the large intestine into mild acids that draw water into the colon, which helps soften the stools. It may take up to 48 hours before you have a bowel movement after taking lactulose.

The chemical name for Lactulose is 4-O-β-D-galactopyranosyl-D-fructofuranose. It has the following structural formula

Lactulose Side Effects
  • Gaseous distention
  • Belching, flatulence
  • Borborygmi
  • Abdominal discomfort (e.g., cramping).
  • Dehydration and hyponatremia in infants

Lactulose Contraindications
Since Lactulose solution contains galactose it is contraindicated in patients who require a low galactose diet.

What special precautions should I follow Before taking lactulose?
  • Tell your doctor and pharmacist if you are allergic to lactulose or any other drugs.
  • Tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antacids, antibiotics including neomycin (Mycifradin), and other laxatives.
  • Tell your doctor if you have diabetes or require a low-lactose diet.
  • Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking lactulose, call your doctor.
  • If you are having surgery or tests on your colon or rectum, tell the doctor that you are taking lactulose.

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